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DeCS
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Descriptor English:
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Mediator Complex
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Descriptor Spanish:
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Complejo Mediador
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Descriptor Portuguese:
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Complexo Mediador
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Synonyms English:
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Mediator Like Complex
Mediator Like Complexes
Mediator Transcription Complex
Mediator-Like Complex
Mediator-Like Complexes
TR-Associated Protein (TRAP) Complex
TRAP (Thyroid Hormone Associated Protein) Complex
Thyroid Hormone Associated Protein Complex
Thyroid Hormone-Associated Protein Complex
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Tree Number:
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D05.500.374
D12.644.360.024.309
D12.776.157.057.072
D12.776.476.024.388
D12.776.660.551
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Definition English:
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A large protein complex which acts as a signaling adaptor protein that allows communication between the various regulatory and functional components of GENETIC TRANSCRIPTION including DNA POLYMERASE II; GENERAL TRANSCRIPTION FACTORS; and TRANSCRIPTION FACTORS that are bound to upstream ENHANCER ELEMENTS. The mediator complex was originally studied in YEAST where at least 21 subunits were identified. Many of the yeast subunits are homologs to proteins in higher organisms that are found associated with specific nuclear receptors such as THYROID HORMONE RECEPTORS and VITAMIN D RECEPTORS. |
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History Note English:
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2010; for TRAP (THYROID HORMONE ASSOCIATED PROTEIN) COMPLEX, TR-ASSOCIATED PROTEIN (TRAP) COMPLEX and THYROID HORMONE-ASSOCIATED PROTEIN COMPLEX use MEDIATOR COMPLEX SUBUNIT 1 2003-2009
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Allowable Qualifiers English:
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Record Number:
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53573
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Unique Identifier:
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D056892
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Occurrence in VHL:
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Similar:
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DeCS
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